Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856588 | 0.83 | PRKAB2 (0.34) | MAPTMTNR1AMTNR1BCYP1A2GAA | |
| SCHEMBL9856089 | 0.80 | ACACB (0.40) | SLC7A5MAPTMTNR1AMTNR1B | |
| SCHEMBL10795235 | 0.79 | HTT (0.33) | SLC6A4MAPTCYP1A2GAACYP2D6 | |
| SCHEMBL9856170 | 0.77 | CA12 (0.44) | SLC6A4MAPTCYP1A2GAA | |
| SCHEMBL9856269 | 0.77 | TAAR1 (0.44) | CYP1A2CYP2D6 | |
| SCHEMBL10394859 | 0.76 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL10791820 | 0.76 | — | — | |
| SCHEMBL10870164 | 0.74 | — | — | |
| SCHEMBL10870168 | 0.74 | — | — | |
| SCHEMBL10789684 | 0.72 | LTA4H (0.44) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |