Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856284 | 0.81 | CA2 (0.43) | MAOAMAOBSLC6A4CA12CA1 | |
| SCHEMBL10394300 | 0.80 | SLC6A4 (0.50) | MAOAMAOBSLC6A4HPGD | |
| SCHEMBL9856269 | 0.77 | TAAR1 (0.44) | — | |
| SCHEMBL3667550 | 0.77 | ALDH1A1 (0.48) | MAOAMAOBSLC6A4CA12CA1 | |
| SCHEMBL11309197 | 0.76 | MAPK1 (0.42) | MAOASLC6A4TSHR | |
| SCHEMBL2155058 | 0.75 | MEN1 (0.49) | MAOAMAOBSLC6A4LMNA | |
| SCHEMBL9855943 | 0.74 | MAOA (0.39) | MAOAMAOBSLC6A4CA12CA1 | |
| SCHEMBL9856172 | 0.74 | HPGD (0.40) | MAOAMAOBHPGDTSHR | |
| SCHEMBL9856153 | 0.73 | LMNA (0.41) | HPGDLMNA | |
| SCHEMBL9856024 | 0.73 | LMNA (0.44) | HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |