Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.41 |
| ▸ | HTT | P42858 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856024 | 0.96 | LMNA (0.44) | LMNAHTTMAPTALOX12MEN1 | |
| SCHEMBL9855981 | 0.83 | MAPT (0.40) | LMNAHTTMAPTALOX12MEN1 | |
| SCHEMBL10394255 | 0.83 | USP2 (0.37) | HTTMAPTMEN1KMT2AMTNR1A | |
| SCHEMBL9856660 | 0.82 | MAPT (0.45) | LMNAHTTMAPTALOX12MEN1 | |
| SCHEMBL9856462 | 0.78 | USP2 (0.40) | HTTMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL9856021 | 0.78 | MTNR1A (0.44) | LMNAHTTMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL9856226 | 0.75 | MTNR1A (0.44) | LMNAHTTKMT2AMTNR1AMTNR1B | |
| SCHEMBL9856284 | 0.73 | CA2 (0.43) | LMNAHTTMAPTALOX12MEN1 | |
| SCHEMBL9856352 | 0.73 | MAOA (0.42) | LMNAHPGD | |
| SCHEMBL10394859 | 0.71 | MTNR1A (0.44) | LMNAHTTMTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |
| EP-0169169-B1 | NOVEL AROMATIC COMPOUNDS | SANDOZ AG (CH) | 1990-10-17 | — | — | EP | disclosed |
| EP-0169169-A2 | Novel aromatic compounds | SANDOZ AG (CH) | 1986-01-22 | — | — | EP | disclosed |