Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | TK1 | P04183 | 3/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157298 | 0.89 | TK1 (0.57) | TK1ABCG2ABCB1 | |
| SCHEMBL9011675 | 0.89 | TK1 (0.57) | TK1ABCG2ABCB1 | |
| SCHEMBL9156285 | 0.89 | TK1 (0.57) | TK1ABCG2ABCB1 | |
| SCHEMBL4277164 | 0.89 | LMNA (0.70) | LMNASMN1; SMN2TYMSTK1 | |
| SCHEMBL4277166 | 0.89 | LMNA (0.70) | LMNASMN1; SMN2TYMSTK1 | |
| SCHEMBL9083560 | 0.88 | TK2 (0.50) | TK1 | |
| SCHEMBL9331077 | 0.88 | TK1 (0.56) | LMNASMN1; SMN2TK1ABCG2ABCB1 | |
| SCHEMBL9331081 | 0.88 | TK1 (0.56) | LMNASMN1; SMN2TK1ABCG2ABCB1 | |
| SCHEMBL8329362 | 0.87 | LMNA (0.55) | LMNASMN1; SMN2TYMSTK1ABCG2 | |
| SCHEMBL570200 | 0.87 | LMNA (0.55) | LMNASMN1; SMN2TYMSTK1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409227-A2 | Pyrimidine nucleosides, their preparation and pharmaceutical preparations | MATTHES, Eckart, Dr. (DE) | 1991-01-23 | — | — | EP | disclosed |