Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 5/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL9856725 | 0.82 | MEN1 (0.36) | MEN1KMT2AMAPTTSHRLMNA | |
| SCHEMBL11072867 | 0.59 | TNF (0.47) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL11078352 | 0.59 | CYP1A2 (0.44) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL9856989 | 0.59 | SLC6A2 (0.46) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL23095838 | 0.59 | PPARG (0.46) | GAAMAPTLMNANPSR1PPARG | |
| SCHEMBL11076821 | 0.58 | ALOX15 (0.42) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL27918600 | 0.58 | LMNA (0.44) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL10511897 | 0.58 | L3MBTL1 (0.44) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL2903384 | 0.57 | L3MBTL1 (0.55) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL18486482 | 0.57 | POLB (0.59) | MEN1KMT2AGAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |