Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL9856985 | 0.77 | SLC6A2 (0.43) | SLC6A2SLC6A4KCNH2SLC6A3ALDH1A1 | |
| SCHEMBL5815188 | 0.70 | LMNA (0.48) | ALDH1A1LMNAMAPTPOLBADRB2 | |
| SCHEMBL9856935 | 0.68 | SLC6A2 (0.49) | SLC6A2SLC6A4KCNH2SLC6A3LMNA | |
| SCHEMBL9856790 | 0.68 | HPGD (0.39) | SLC6A2SLC6A4ALDH1A1MAPTNPSR1 | |
| SCHEMBL28165249 | 0.67 | LMNA (0.49) | SLC6A2SLC6A4KCNH2SLC6A3LMNA | |
| SCHEMBL28165251 | 0.67 | LMNA (0.49) | SLC6A2SLC6A4KCNH2SLC6A3LMNA | |
| SCHEMBL11217648 | 0.65 | LTB4R (0.47) | PPARGKMT2A | |
| SCHEMBL28575431 | 0.65 | ALDH1A1 (0.50) | SLC6A2SLC6A4KCNH2SLC6A3ALDH1A1 | |
| SCHEMBL7406457 | 0.65 | SLC6A2 (0.45) | SLC6A2SLC6A4KCNH2SLC6A3ALDH1A1 | |
| SCHEMBL8084869 | 0.64 | L3MBTL1 (0.57) | MAPTNPSR1PPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |