Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | EEF2K | O00418 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857073 | 0.76 | SLC6A9 (0.57) | SLC6A9PPARGPPARAALDH1A1SLC6A4 | |
| SCHEMBL9857350 | 0.75 | SLC6A9 (0.67) | SLC6A9SLC6A4HRH3HTR2AHRH1 | |
| SCHEMBL9856532 | 0.75 | SLC6A4 (0.58) | SLC6A9ALDH1A1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13204407 | 0.74 | SLC6A9 (0.63) | SLC6A9SLC6A4SLC6A2SLC6A3MEN1 | |
| Hydrochloric Acid SCHEMBL9857132 | 0.74 | SLC6A4 (0.59) | SLC6A9ALDH1A1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9733971 | 0.72 | SLC6A9 (0.50) | SLC6A9PPARGPPARAALDH1A1SLC6A4 | |
| SCHEMBL9857070 | 0.70 | SLC6A9 (0.52) | SLC6A9PPARGPPARAALDH1A1CNR1 | |
| SCHEMBL9857396 | 0.69 | SLC6A4 (0.54) | SLC6A9PPARGPPARAALDH1A1SLC6A4 | |
| SCHEMBL13821690 | 0.67 | SLC6A9 (0.46) | SLC6A9ALDH1A1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6491675 | 0.66 | FFAR1 (0.55) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0318233-A2 | Improvements in or relating to serotonin and norepinephrine uptake inhibitors | ELI LILLY AND COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |