SCHEMBL9856893

SCHEMBL9856893

Cc1ccc(-c2ccc3ccccc3c2C(=O)c2c(-c3ccc(C)cc3C)ccc3ccccc23)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.43
CYP1A2 P05177 3/20 0.43
THRB P10828 1/20 0.43
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
CNR2 P34972 3/20 0.41
TDP1 Q9NUW8 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
ALDH1A1 P00352 4/20 0.40
HPGD P15428 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HSD17B10 Q99714 2/20 0.40
ELANE P08246 1/20 0.40
GLA P06280 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9857431 0.84 CYP1A2 (0.44) CYP2A6CYP1A2THRBCNR2ALDH1A1
SCHEMBL9857366 0.81 GPR84 (0.43) CYP1A2TDP1ALDH1A1HPGDKDM4E
SCHEMBL9856903 0.80 WDR5 (0.47) CYP2A6CYP1A2THRBCNR2ALDH1A1
SCHEMBL6548332 0.80 CA12 (0.54) CYP2A6CYP1A2THRBCA12CA1
SCHEMBL6253078 0.79 THRB (0.49) CYP2A6CYP1A2THRBTDP1MAOA
SCHEMBL230034 0.76 TSHR (0.54) CYP2A6CYP1A2TDP1ALDH1A1HPGD
SCHEMBL29626829 0.76 TSHR (0.54) CYP2A6CYP1A2TDP1ALDH1A1HPGD
SCHEMBL18322335 0.76 GSTP1 (0.52) CYP1A2ALDH1A1HPGDKDM4EMEN1
SCHEMBL5491328 0.76 ALDH1A1 (0.49) CYP2A6CYP1A2THRBCA12CA1
SCHEMBL9856898 0.75 ERN1 (0.47) CYP2A6CYP1A2THRBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0426846-A1 FLUORINATED-AROMATIC SULFONIC ACID CATALYST, PROCESS FOR ITS PRODUCTION, AND ITS USE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-15 EP disclosed