Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856810 | 0.81 | TSHR (0.34) | MEN1KMT2ATSHR | |
| SCHEMBL9856975 | 0.81 | ALDH1A1 (0.34) | MEN1KMT2ATSHR | |
| SCHEMBL9730290 | 0.78 | TSHR (0.38) | MEN1KMT2ATSHR | |
| SCHEMBL9347640 | 0.73 | TSHR (0.44) | MEN1KMT2ATSHR | |
| SCHEMBL10779090 | 0.72 | TSHR (0.39) | MEN1KMT2ATSHR | |
| SCHEMBL12787299 | 0.71 | TSHR (0.38) | MEN1KMT2ATSHR | |
| SCHEMBL23529640 | 0.71 | TSHR (0.41) | MEN1KMT2ATSHR | |
| SCHEMBL2915808 | 0.71 | TSHR (0.41) | MEN1KMT2ATSHR | |
| SCHEMBL29772371 | 0.71 | TSHR (0.41) | MEN1KMT2ATSHR | |
| SCHEMBL2915807 | 0.71 | TSHR (0.41) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436851-A1 | Compounds active as inhibitors of the enzyme HMG-CoA reductase and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1991-07-17 | — | — | EP | disclosed |