Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | POLG | P54098 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.34 |
| ▸ | PI4KA | P42356 | 2/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857673 | 0.90 | FDPS (0.33) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9683408 | 0.88 | FAP (0.35) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9858312 | 0.81 | FGFR1 (0.49) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9683429 | 0.79 | FAP (0.34) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9857984 | 0.78 | FAP (0.43) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9858419 | 0.78 | — | — | |
| SCHEMBL9684076 | 0.77 | FDPS (0.34) | — | |
| SCHEMBL9858133 | 0.75 | FGFR1 (0.47) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9857545 | 0.75 | SLC22A6 (0.44) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9857986 | 0.75 | SLC22A6 (0.45) | FAPSLC22A6ABCB11POLA1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | disclosed |