Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | POLG | P54098 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857992 | 0.90 | FAP (0.41) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL9684076 | 0.88 | FDPS (0.34) | FDPS | |
| SCHEMBL9858419 | 0.84 | — | — | |
| SCHEMBL9685495 | 0.79 | FDPS (0.33) | FDPS | |
| SCHEMBL9683408 | 0.77 | FAP (0.35) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL9857662 | 0.77 | ABCB11 (0.35) | FDPSABCB11POLA1POLGFAP | |
| SCHEMBL9857669 | 0.75 | ABCB11 (0.36) | FDPSABCB11POLA1POLGFAP | |
| SCHEMBL9417142 | 0.73 | FDPS (0.41) | FDPSABCB11POLA1POLGFAP | |
| SCHEMBL9858079 | 0.72 | FDPS (0.40) | FDPSABCB11POLA1POLGFAP | |
| SCHEMBL9858044 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | disclosed |