Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | POLG | P54098 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 4/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684076 | 0.89 | FDPS (0.34) | HSP90AA1HSP90AB1 | |
| SCHEMBL9857992 | 0.88 | FAP (0.41) | FAPABCB11POLA1POLGSLC22A6 | |
| SCHEMBL9683429 | 0.86 | FAP (0.34) | FAPABCB11POLA1POLGSLC22A6 | |
| SCHEMBL9683749 | 0.80 | FGFR1 (0.42) | SLC22A6PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9857673 | 0.77 | FDPS (0.33) | FAPABCB11POLA1POLGSLC22A6 | |
| SCHEMBL9683414 | 0.76 | ABCB11 (0.36) | FAPABCB11POLA1POLGSLC22A6 | |
| SCHEMBL9685495 | 0.76 | FDPS (0.33) | — | |
| SCHEMBL9684256 | 0.74 | — | — | |
| SCHEMBL9683794 | 0.73 | CYP3A4 (0.41) | SLC22A6PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9685082 | 0.72 | ABCB11 (0.35) | FAPABCB11POLA1POLGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |