Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 5/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Luxabendazole SCHEMBL29765623 | 0.89 | TUBB4A (0.56) | ENPP1ENPP3METCDK9TUBB4A | |
| Luxabendazole SCHEMBL6055930 | 0.89 | TUBB4A (0.56) | ENPP1ENPP3METCDK9TUBB4A | |
| SCHEMBL5036233 | 0.86 | ENPP3 (0.55) | ENPP1ENPP3METCDK9TUBB4A | |
| SCHEMBL5037860 | 0.86 | MET (0.46) | ENPP1ENPP3METCDK9TUBB4A | |
| SCHEMBL5036108 | 0.81 | RAB9A (0.50) | ENPP1ENPP3RAB9ASMN1; SMN2TP53 | |
| Luxabendazole SCHEMBL321908 | 0.81 | TUBB4A (0.67) | METCDK9TUBB4ATUBBTUBA3C | |
| SCHEMBL11860103 | 0.80 | MET (0.60) | METCDK9TUBB4ATUBBTUBA3C | |
| Luxabendazole SCHEMBL1193261 | 0.80 | TUBB4A (0.66) | METCDK9TUBB4ATUBBTUBA3C | |
| SCHEMBL5036539 | 0.80 | ENPP3 (0.50) | ENPP1ENPP3NPC1RAB9AENPP2 | |
| SCHEMBL10738488 | 0.79 | TUBB4A (0.54) | METCDK9TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279343-B1 | COMBINATIONS OF ANTHELMINTICALLY ACTIVE AGENTS | BAYER AG (DE) | 1991-06-05 | — | — | EP | disclosed |