Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30341701 | 0.94 | APP (0.60) | ALDH1A1KMT2AMEN1APPHPGD | |
| SCHEMBL348043 | 0.94 | APP (0.60) | ALDH1A1KMT2AMEN1APPHPGD | |
| SCHEMBL6546267 | 0.91 | POLB (0.57) | AMY1AALDH1A1LMNAKMT2AAPP | |
| SCHEMBL9587052 | 0.88 | CYP1A1 (0.65) | AMY1AALDH1A1LMNAAPPHPGD | |
| SCHEMBL9587050 | 0.88 | CYP1A1 (0.65) | AMY1AALDH1A1LMNAAPPHPGD | |
| SCHEMBL9861768 | 0.86 | SMN1; SMN2 (0.58) | ALDH1A1LMNAKMT2AMEN1APP | |
| SCHEMBL752160 | 0.85 | ALDH1A1 (0.65) | AMY1AALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL20058837 | 0.85 | AMY1A (0.60) | AMY1AALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL29377794 | 0.85 | ALDH1A1 (0.65) | AMY1AALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL15963939 | 0.84 | APP (0.58) | AMY1AALDH1A1LMNAAPPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104761537-A | Preparation method of beta-chloro-1,3-dithiane derivative | UNIV LANZHOU | 2015-07-08 | — | — | CN | claimed |
| US-11634375-B2 | Prenylated hydroxystilbenes | Kynan Duke IP, LLC (US) | 2023-04-25 | — | — | US | disclosed |
| US-20220380285-A1 | PRENYLATED HYDROXYSTILBENES | Kynan Duke IP, LLC (US) | 2022-12-01 | — | — | US | disclosed |
| US-11352310-B2 | Prenylated hydroxystilbenes | Kynan Duke IP, LLC (US) | 2022-06-07 | — | — | US | disclosed |
| US-20200331833-A1 | PRENYLATED HYDROXYSTILBENES | THE UNIVERSITY OF SYDNEY (AU) | 2020-10-22 | — | — | US | disclosed |
| US-10696615-B2 | Prenylated hydroxystilbenes | THE UNIVERSITY OF SYDNEY (AU) | 2020-06-30 | — | — | US | disclosed |
| US-20190194105-A1 | PRENYLATED HYDROXYSTILBENES | THE UNIVERSITY OF SYDNEY (AU) | 2019-06-27 | — | — | US | disclosed |
| US-10196335-B2 | Prenylated hydroxystilbenes | THE UNIVERSITY OF SYDNEY (AU) | 2019-02-05 | — | — | US | disclosed |
| CN-104761537-B | Preparation method of beta-chloro-1,3-dithiane derivative | 兰州大学 | 2017-02-15 | — | — | CN | disclosed |
| US-20150307429-A1 | PRENYLATED HYDROXYSTILBENES | Kynan Duke IP, LLC | 2015-10-29 | — | — | US | disclosed |
| CN-104761537-A | Preparation method of beta-chloro-1,3-dithiane derivative | UNIV LANZHOU | 2015-07-08 | — | — | CN | disclosed |
| US-20140121213-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | GLAXO GROUP LIMITED (GB) | 2014-05-01 | — | — | US | disclosed |
| EP-2709975-A1 | PRENYLATED HYDROXYSTILBENES | THE UNIVERSITY OF SYDNEY (AU) | 2014-03-26 | — | — | EP | disclosed |
| US-20130023541-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | GLAXO GROUP LIMITED | 2013-01-24 | — | — | US | disclosed |
| US-20130023541-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | GLAXO GROUP LIMITED | 2013-01-24 | — | — | US | disclosed |
| WO-2012149608-A1 | PRENYLATED HYDROXYSTILBENES | THE UNIVERSITY OF SIDNEY (AU) | 2012-11-08 | — | — | WO | disclosed |
| US-20070037851-A1 | Inhibits binding of CCR3 ligands such as eotaxins to their target cells; inhibits physiological effects of binding; therapeutic and prophylactic agents for asthma, rhinitis, dermatitis, urticaria, conjunctivitis, inflammatory bowel; tissue infiltration of eosinophils, basophils, activated T cells | TEIJIN LIMITED, A JAPANESE BODY CORPORATE (JP) | 2007-02-15 | — | — | US | disclosed |
| US-20070032525-A1 | Piperidine derivatives having ccr3 antagonism | TEIJIN LIMITED, A JAPANESE BODY CORPORATE (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196335-B2 | Prenylated hydroxystilbenes | HMGB2, CYP51A1, CYP8B1 | AMY1A 4533/4885ALDH1A1 1145/4885LMNA 1076/4885 |
| US-20200331833-A1 | PRENYLATED HYDROXYSTILBENES | HSD11B1, HSD3B1, CYP8B1 | AMY1A 1021/4885ALDH1A1 314/4885LMNA 114/4885 |
| US-20070032525-A1 | Piperidine derivatives having ccr3 antagonism | CCR3, CCR1, CCR4 | AMY1A 4071/4885ALDH1A1 451/4885LMNA 2459/4885 |
| US-20130023541-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | KCNB1, KCNB2, SCNN1B | AMY1A 4770/4885ALDH1A1 2656/4885LMNA 611/4885 |
| US-20070037851-A1 | Inhibits binding of CCR3 ligands such as eotaxins to their target cells; inhibits physiological effects of binding; therapeutic and prophylactic agents for asthma, rhinitis, dermatitis, urticaria, conjunctivitis, inflammatory bowel; tissue infiltration of eosinophils, basophils, activated T cells | CCR3, CCR1, CCR4 | AMY1A 3445/4885ALDH1A1 486/4885LMNA 4010/4885 |
| US-20140121213-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | KCNB1, SCNN1B, TRPV1 | AMY1A 4719/4885ALDH1A1 2495/4885LMNA 816/4885 |
| US-20220380285-A1 | PRENYLATED HYDROXYSTILBENES | HSD11B1, HSD3B1, CYP8B1 | AMY1A 1021/4885ALDH1A1 314/4885LMNA 114/4885 |
| US-20150307429-A1 | PRENYLATED HYDROXYSTILBENES | HMGB2, CYP51A1, CYP8B1 | AMY1A 4533/4885ALDH1A1 1145/4885LMNA 1076/4885 |
| US-10696615-B2 | Prenylated hydroxystilbenes | HSD11B1, CYP8B1, NR1H2 | AMY1A 535/4885ALDH1A1 145/4885LMNA 167/4885 |
| US-11352310-B2 | Prenylated hydroxystilbenes | HSD11B1, HSD3B1, CYP8B1 | AMY1A 1021/4885ALDH1A1 314/4885LMNA 114/4885 |
| US-20190194105-A1 | PRENYLATED HYDROXYSTILBENES | HSD11B1, CYP8B1, NR1H2 | AMY1A 535/4885ALDH1A1 145/4885LMNA 167/4885 |
| US-11634375-B2 | Prenylated hydroxystilbenes | HCLS1, IWS1, UTS2R | AMY1A 3927/4885ALDH1A1 513/4885LMNA 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.