Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862019 | 0.86 | LMNA (0.37) | TSHRMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL10498325 | 0.80 | ALDH1A1 (0.38) | THRBTSHRALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL9862091 | 0.77 | THRB (0.36) | THRBTSHRALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL28678971 | 0.75 | MAPK1 (0.52) | PIN1POLBTSHRMEN1KMT2A | |
| SCHEMBL7692315 | 0.75 | CYP2C19 (0.33) | THRBTSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8883023 | 0.73 | MAPK1 (0.53) | THRBTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL28678972 | 0.70 | MAPK1 (0.48) | PIN1POLBTSHRMEN1KMT2A | |
| SCHEMBL9847912 | 0.70 | ALDH1A1 (0.46) | THRBTSHRALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL9242598 | 0.69 | ALDH1A1 (0.50) | THRBTSHRALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL18051656 | 0.68 | THRB (0.47) | THRBPOLBTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423767-A2 | Thermoplastic resin composition and method for preparing the same | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-04-24 | — | — | EP | disclosed |