Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498325 | 0.88 | ALDH1A1 (0.38) | THRBALDH1A1TSHRHPGDSOAT1 | |
| SCHEMBL9862000 | 0.77 | GSTO1 (0.36) | THRBALDH1A1TSHRCYP3A4MAPK1 | |
| SCHEMBL9242598 | 0.76 | ALDH1A1 (0.50) | THRBALDH1A1TSHRHPGDSOAT1 | |
| SCHEMBL9862019 | 0.73 | LMNA (0.37) | ALDH1A1TSHRHPGDHIF1ASMN1; SMN2 | |
| SCHEMBL9847912 | 0.73 | ALDH1A1 (0.46) | THRBALDH1A1TSHRHPGDSOAT1 | |
| SCHEMBL8892386 | 0.71 | THRB (0.41) | THRBALDH1A1TSHRHPGDTP53 | |
| SCHEMBL10715928 | 0.70 | THRB (0.36) | THRBTSHRHPGD | |
| SCHEMBL7683837 | 0.70 | THRB (0.36) | THRB | |
| SCHEMBL27897713 | 0.68 | ALDH1A1 (0.55) | THRBALDH1A1TSHRHPGDSOAT1 | |
| Acrylic Acid Ethyl Ester SCHEMBL23607549 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423767-A2 | Thermoplastic resin composition and method for preparing the same | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-04-24 | — | — | EP | disclosed |