Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.41 |
| ▸ | ELOC | Q15369 | 1/20 | 0.41 |
| ▸ | ELOB | Q15370 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865613 | 0.89 | ALDH1A1 (0.34) | VHLELOCELOBALDH1A1 | |
| SCHEMBL14591138 | 0.70 | — | — | |
| SCHEMBL9865054 | 0.69 | ALDH1A1 (0.32) | HTTALDH1A1 | |
| SCHEMBL10514566 | 0.68 | VHL (0.41) | VHLELOCELOBKDM4EHTT | |
| SCHEMBL333300 | 0.63 | MAPT (0.42) | KDM4EALDH1A1 | |
| SCHEMBL3129135 | 0.63 | HSD17B10 (0.39) | KDM4EALDH1A1PTPRC | |
| SCHEMBL29414923 | 0.63 | VHL (0.56) | VHLELOCELOBKDM4EHTT | |
| SCHEMBL7417 | 0.63 | VHL (0.56) | VHLELOCELOBKDM4EHTT | |
| SCHEMBL566902 | 0.62 | TDP2 (0.39) | VHLELOCELOBKDM4EHTT | |
| SCHEMBL566998 | 0.61 | MAPK1 (0.43) | VHLELOCELOBKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045561-A | Substituted furan sulfonamides as antiglaucoma agents | MERCK & CO., INC. (US) | 1991-09-03 | — | — | US | disclosed |