Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866436 | 0.76 | KDM4E (0.43) | ALDH1A1PBRM1 | |
| SCHEMBL22905751 | 0.72 | HTR2C (0.43) | ALDH1A1MAPTPBRM1MEN1LMNA | |
| SCHEMBL9143961 | 0.70 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLBSTAT3 | |
| SCHEMBL9864191 | 0.69 | VHL (0.41) | ALDH1A1HTT | |
| SCHEMBL9864692 | 0.67 | CA2 (0.32) | — | |
| SCHEMBL9865613 | 0.67 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL9866122 | 0.65 | POLB (0.30) | POLB | |
| SCHEMBL762215 | 0.60 | — | — | |
| SCHEMBL15606100 | 0.58 | HTR2C (0.39) | ALDH1A1MAPTLMNAKMT2ASTAT3 | |
| SCHEMBL13677130 | 0.58 | ACHE (0.46) | POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045561-A | Substituted furan sulfonamides as antiglaucoma agents | MERCK & CO., INC. (US) | 1991-09-03 | — | — | US | disclosed |