Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865624 | 0.81 | KDM4E (0.59) | — | |
| SCHEMBL9866791 | 0.72 | LMNA (0.45) | SMN1; SMN2HPGDMEN1KMT2APOLB | |
| SCHEMBL1578277 | 0.71 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2HPGDRECQL | |
| SCHEMBL29639804 | 0.71 | L3MBTL1 (0.70) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9865051 | 0.70 | SCN5A (0.59) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9865046 | 0.70 | SCN5A (0.59) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL10829144 | 0.70 | GAA (0.64) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL4629192 | 0.69 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL7296910 | 0.69 | ELANE (0.44) | RAB9AHPGDL3MBTL1KMT2ATSHR | |
| SCHEMBL3446802 | 0.69 | MTNR1A (0.73) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |