Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866193 | 0.99 | HTT (0.58) | HTTSMN1; SMN2RAB9ATGM2MEN1 | |
| SCHEMBL9879968 | 0.96 | HTT (0.60) | HTTSMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL14264247 | 0.89 | HTT (0.64) | HTTSMN1; SMN2TGM2KDM4EHDAC3 | |
| SCHEMBL10444691 | 0.88 | HDAC6 (0.49) | HTTRAB9ATGM2MEN1KMT2A | |
| SCHEMBL9867129 | 0.88 | HDAC6 (0.49) | HTTRAB9ATGM2MEN1KMT2A | |
| SCHEMBL9335791 | 0.87 | HTT (0.49) | HTTRAB9AMEN1KMT2AHDAC3 | |
| SCHEMBL9865134 | 0.83 | HTT (0.53) | HTTSMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL31391106 | 0.81 | CA1 (0.62) | HTTSMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL6400257 | 0.81 | MGLL (0.72) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9866697 | 0.80 | CA1 (0.64) | HTTSMN1; SMN2RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |