Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10369197 | 0.91 | SMN1; SMN2 (0.36) | MAPTHPGDUSP7SMN1; SMN2NPC1 | |
| SCHEMBL9865076 | 0.88 | ALDH1A1 (0.42) | MAPTHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9865184 | 0.86 | USP7 (0.39) | MAPTHPGDUSP7SMN1; SMN2NPC1 | |
| SCHEMBL9865166 | 0.79 | USP7 (0.40) | USP7SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL9865250 | 0.76 | LMNA (0.42) | MAPTHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9865195 | 0.74 | LMNA (0.52) | MAPTHPGDNPC1RAB9ALMNA | |
| SCHEMBL9866055 | 0.74 | LMNA (0.42) | MAPTHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9865622 | 0.74 | ALDH1A1 (0.42) | MAPTHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9864883 | 0.69 | — | — | |
| SCHEMBL9864771 | 0.67 | SRC (0.36) | MAPTHPGDNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |