SCHEMBL9865337

SCHEMBL9865337

CC(C)N(C)S(=O)(=O)c1cccc(F)n1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.32
MAPT P10636 1/20 0.32
SCN1A P35498 2/20 0.32
SCN5A Q14524 2/20 0.32
SCN8A Q9UQD0 2/20 0.32
AGER Q15109 1/20 0.32
FFAR2 O15552 1/20 0.31
HRH1 P35367 1/20 0.30
ALOX5 P09917 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9866776 0.84 SMN1; SMN2 (0.37) MAPTSCN1ASCN5ASCN8AFFAR2
SCHEMBL9866361 0.78 KMT2A (0.35) MAPTSCN1ASCN5ASCN8AALOX5
SCHEMBL9869217 0.78 KDM4E (0.33) MAPT
SCHEMBL9869170 0.76 KDM4E (0.35) HSP90AA1MAPTALDH1A1HPGD
SCHEMBL9865651 0.74 HCAR1 (0.33) ALDH1A1HPGD
SCHEMBL12319048 0.74 LOX (0.41) MAPTSCN1ASCN5ASCN8AALOX5
SCHEMBL9865871 0.73 L3MBTL1 (0.41) ALDH1A1
SCHEMBL9867676 0.73 PDE4A (0.37)
SCHEMBL9866654 0.72 ALDH1A1 (0.38) SCN1ASCN5ASCN8AFFAR2ALDH1A1
SCHEMBL9866930 0.72 ALDH1A1 (0.34) ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5071987-A Quinoline dyes; colorfastness BASF AKTIENGESELLSCHAFT (DE) 1991-12-10 US disclosed
US-4987141-A DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-22 US disclosed
EP-0356029-A2 Insecticidal compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-02-28 EP disclosed