Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 3/20 | 0.53 |
| ▸ | HTR7 | P34969 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10445024 | 0.98 | HTR1A (0.51) | HTR1AHTR2AHTR2CHTR7DRD3 | |
| Hydrochloric Acid SCHEMBL10445023 | 0.98 | HTR1A (0.51) | HTR1AHTR2AHTR2CHTR7DRD3 | |
| SCHEMBL9866558 | 0.84 | HRH3 (0.45) | HRH3 | |
| Hydrochloric Acid SCHEMBL9865627 | 0.84 | HRH3 (0.46) | HRH3 | |
| Hydrochloric Acid SCHEMBL9865621 | 0.84 | HRH3 (0.46) | HRH3 | |
| SCHEMBL9866508 | 0.83 | HTR1A (0.43) | HTR1AHTR2AHTR2CHTR7DRD3 | |
| SCHEMBL9865443 | 0.81 | MAPT (0.43) | HTR1AHTR2AHTR2CHTR7DRD3 | |
| SCHEMBL9868353 | 0.81 | SLC11A2 (0.49) | HTR1AHTR2AHTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL9866019 | 0.77 | DRD2 (0.44) | DRD2HRH3 | |
| Hydrochloric Acid SCHEMBL9866011 | 0.77 | DRD2 (0.44) | DRD2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |