Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866508 | 0.89 | HTR1A (0.43) | KMT2AHTR1ADRD4HTR2AHTR2C | |
| SCHEMBL9868353 | 0.85 | SLC11A2 (0.49) | MAPTKMT2AHTR1AHTR2AHTR2C | |
| SCHEMBL9865351 | 0.81 | HTR1A (0.53) | HTR1ADRD4HTR2AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL10445024 | 0.80 | HTR1A (0.51) | HTR1ADRD4HTR2AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL10445023 | 0.80 | HTR1A (0.51) | HTR1ADRD4HTR2AHTR2CHTR7 | |
| SCHEMBL9867723 | 0.78 | CD274 (0.43) | ACHEMIFBCHE | |
| Hydrochloric Acid SCHEMBL9603029 | 0.74 | MAPK14 (0.40) | MAPTKMT2ACHRNA7HTR1AHRH3 | |
| SCHEMBL10366227 | 0.72 | CD274 (0.50) | HTR1ADRD4HTR2AHTR2CHTR7 | |
| Maleic Acid SCHEMBL9602819 | 0.71 | MAPK14 (0.36) | MAPTHTR1AHRH3KDM4EPOLB | |
| SCHEMBL9879719 | 0.68 | ACHE (0.43) | KMT2AHRH3MEN1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |