Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866336 | 0.87 | LMNA (0.54) | NR1H4LMNAMEN1KMT2ARAB9A | |
| SCHEMBL9335708 | 0.83 | NR1H4 (0.49) | NR1H4PAX8LMNAMEN1KMT2A | |
| SCHEMBL9867345 | 0.83 | NAMPT (0.52) | NR1H4PAX8LMNAKDM1AMAOA | |
| SCHEMBL7906614 | 0.81 | SENP1 (0.46) | NR1H4PAX8LMNAMEN1KMT2A | |
| SCHEMBL9865584 | 0.81 | NAMPT (0.60) | NR1H4PAX8LMNAHDAC3KDM1A | |
| SCHEMBL9335795 | 0.81 | CTSL (0.51) | KDM1AMAOAKDM1BRCOR1 | |
| SCHEMBL9865730 | 0.81 | CTSL (0.51) | KDM1AMAOAKDM1BRCOR1 | |
| SCHEMBL9866050 | 0.81 | GAA (0.54) | LMNAMEN1KMT2ARAB9AGAA | |
| SCHEMBL9865717 | 0.80 | KDM1A (0.48) | NR1H4PAX8LMNAKDM1AMAOA | |
| SCHEMBL9864590 | 0.80 | PAX8 (0.52) | NR1H4PAX8LMNAKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |