Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868136 | 0.88 | ALDH1A1 (0.49) | ALDH1A1TSHRGLATDP1LMNA | |
| SCHEMBL9867699 | 0.83 | ALDH1A1 (0.40) | ALDH1A1TSHRSMN1; SMN2MAPK1KDM4E | |
| Phosphoric Acid SCHEMBL9867536 | 0.78 | PTGS1 (0.46) | ALDH1A1TSHRGLATDP1LMNA | |
| SCHEMBL9867999 | 0.73 | PTGS1 (0.49) | ALDH1A1TSHRGLATDP1LMNA | |
| SCHEMBL9867658 | 0.71 | HTR2C (0.44) | ALDH1A1TSHRLMNAKDM4EHSD17B10 | |
| SCHEMBL9867136 | 0.66 | ALDH1A1 (0.42) | ALDH1A1HTTSMN1; SMN2MAPK1HPGD | |
| SCHEMBL9866886 | 0.64 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNAMAPK1KDM4E | |
| SCHEMBL8828408 | 0.63 | KCNH2 (0.48) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL14472858 | 0.58 | RIPK1 (0.43) | ALDH1A1TSHRLMNAKDM4EMAPT | |
| SCHEMBL11478728 | 0.58 | PDE4A (0.41) | ALDH1A1GLAGAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028715-A | 3-(3''-Aminoalkyl)-2-Arylthiazolidine Compounds | SOUTHWEST RESEARCH INSTITUTE (US) | 1991-07-02 | — | — | US | disclosed |