Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865784 | 0.88 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1HTTLMNA | |
| SCHEMBL9867999 | 0.83 | PTGS1 (0.49) | ALDH1A1TSHRTDP1HTTLMNA | |
| SCHEMBL9867658 | 0.81 | HTR2C (0.44) | ALDH1A1TSHRLMNAKDM4E | |
| Phosphoric Acid SCHEMBL9867536 | 0.77 | PTGS1 (0.46) | ALDH1A1TSHRTDP1HTTLMNA | |
| SCHEMBL9867136 | 0.75 | ALDH1A1 (0.42) | ALDH1A1HTTSMN1; SMN2MAPK1MAPT | |
| SCHEMBL8828408 | 0.72 | KCNH2 (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9865569 | 0.72 | DRD2 (0.38) | ALDH1A1TSHRLMNAMAPK1KDM4E | |
| SCHEMBL9866886 | 0.71 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNAMAPK1KDM4E | |
| SCHEMBL14472858 | 0.66 | RIPK1 (0.43) | ALDH1A1TSHRLMNAKDM4EMAPT | |
| SCHEMBL9778828 | 0.65 | TSHR (0.61) | ALDH1A1TSHRGAAPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028715-A | 3-(3''-Aminoalkyl)-2-Arylthiazolidine Compounds | SOUTHWEST RESEARCH INSTITUTE (US) | 1991-07-02 | — | — | US | claimed |