Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867136 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HPGDSMN1; SMN2SCN9A | |
| SCHEMBL9865784 | 0.83 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4EHPGDCASP1 | |
| Phosphoric Acid SCHEMBL9867536 | 0.73 | PTGS1 (0.46) | ALDH1A1HSD17B10KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9868136 | 0.69 | ALDH1A1 (0.49) | ALDH1A1KDM4ESMN1; SMN2MAPK1TSHR | |
| SCHEMBL9867999 | 0.67 | PTGS1 (0.49) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL6606870 | 0.66 | TERT (0.46) | ALDH1A1HSD17B10KDM4EPKMSMN1; SMN2 | |
| SCHEMBL9867658 | 0.66 | HTR2C (0.44) | ALDH1A1HSD17B10KDM4ETSHR | |
| SCHEMBL6608574 | 0.64 | KCNA5 (0.46) | ALDH1A1HSD17B10KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL9866886 | 0.63 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPK1 | |
| SCHEMBL4093709 | 0.63 | TLR9 (0.47) | ALDH1A1HPGDSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028715-A | 3-(3''-Aminoalkyl)-2-Arylthiazolidine Compounds | SOUTHWEST RESEARCH INSTITUTE (US) | 1991-07-02 | — | — | US | disclosed |