Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867699 | 0.86 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HSD17B10SCN9AMAPK1 | |
| SCHEMBL9868136 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL4093709 | 0.73 | TLR9 (0.47) | ALDH1A1HTTSMN1; SMN2CYP3A4MAPT | |
| SCHEMBL9867999 | 0.73 | PTGS1 (0.49) | ALDH1A1HTTHSD17B10MAPTHPGD | |
| SCHEMBL9867658 | 0.72 | HTR2C (0.44) | ALDH1A1TAAR1HSD17B10 | |
| SCHEMBL9866886 | 0.71 | ALDH1A1 (0.47) | ALDH1A1MAPTMAPK1POLB | |
| SCHEMBL6606870 | 0.69 | TERT (0.46) | ALDH1A1SMN1; SMN2HSD17B10MAPTMAPK1 | |
| SCHEMBL6707313 | 0.69 | TLR9 (0.46) | HTTSMN1; SMN2CYP3A4MAPTMAPK1 | |
| SCHEMBL6608574 | 0.69 | KCNA5 (0.46) | ALDH1A1HTTSMN1; SMN2HSD17B10MAPT | |
| Phosphoric Acid SCHEMBL9867536 | 0.68 | PTGS1 (0.46) | ALDH1A1HTTSMN1; SMN2HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028715-A | 3-(3''-Aminoalkyl)-2-Arylthiazolidine Compounds | SOUTHWEST RESEARCH INSTITUTE (US) | 1991-07-02 | — | — | US | claimed |