SCHEMBL9865799

SCHEMBL9865799

COC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)c1cccc(NC(=O)OCc2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.51
KDM1A O60341 1/20 0.47
MAOA P21397 1/20 0.47
KDM1B Q8NB78 1/20 0.47
RCOR1 Q9UKL0 1/20 0.47
ENPP2 Q13822 2/20 0.47
RAB9A P51151 1/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
KMT2A Q03164 1/20 0.46
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46
PPARG P37231 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9865704 0.88 CTSK (0.44) MGLLENPP2ALDH1A1FNTAFNTB
SCHEMBL4256075 0.82 KYNU (0.56) ALDH1A1
SCHEMBL19694832 0.82 KYNU (0.56) ALDH1A1
SCHEMBL19694834 0.82 KYNU (0.56) ALDH1A1
SCHEMBL7145264 0.81 MGLL (0.52) MGLLKDM1AMAOAKDM1BRCOR1
SCHEMBL9866297 0.79 KMT2A (0.43) RAB9AMEN1ALDH1A1KMT2A
SCHEMBL9337552 0.79 ITGB3 (0.49) ALDH1A1KMT2A
SCHEMBL19327506 0.79 KLK5 (0.51) KDM4EALDH1A1
SCHEMBL19327507 0.79 KLK5 (0.51) KDM4EALDH1A1
SCHEMBL9335977 0.79 KMT2A (0.43) RAB9AMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5039805-A Novel benzoic and phenylacetic acid derivatives HOFFMANN-LA ROCHE INC. (US) 1991-08-13 US disclosed