Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865917 | 0.90 | MAOA (0.34) | ACHEHRH3S1PR1S1PR3 | |
| SCHEMBL9601960 | 0.88 | CDK4 (0.34) | ACHES1PR1S1PR3 | |
| SCHEMBL9603188 | 0.88 | MAPT (0.37) | ACHEHRH3 | |
| Hydrochloric Acid SCHEMBL9602310 | 0.87 | S1PR1 (0.33) | ACHES1PR1S1PR3 | |
| Maleic Acid SCHEMBL9866351 | 0.84 | ALDH1A1 (0.33) | S1PR1S1PR3 | |
| Fumaric Acid SCHEMBL9866359 | 0.84 | ALDH1A1 (0.33) | S1PR1S1PR3 | |
| SCHEMBL9867304 | 0.81 | MAOA (0.35) | ACHEHRH3 | |
| SCHEMBL9602137 | 0.80 | S1PR1 (0.32) | ACHES1PR1S1PR3 | |
| SCHEMBL9602515 | 0.79 | ALDH1A1 (0.33) | ACHE | |
| SCHEMBL9868430 | 0.79 | TOP1 (0.35) | ACHEHRH3S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |