Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865917 | 0.90 | MAOA (0.34) | MAOAMAOBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9602515 | 0.90 | ALDH1A1 (0.33) | TOP1GAAACHE | |
| SCHEMBL9602191 | 0.84 | DRD2 (0.32) | MAOBTOP1GAA | |
| Fumaric Acid SCHEMBL9866359 | 0.84 | ALDH1A1 (0.33) | — | |
| Maleic Acid SCHEMBL9866351 | 0.84 | ALDH1A1 (0.33) | — | |
| SCHEMBL9866052 | 0.84 | MCHR1 (0.34) | MAOAMAOBTOP1SMN1; SMN2MEN1 | |
| Fumaric Acid SCHEMBL9602984 | 0.84 | MAPT (0.33) | SMN1; SMN2MEN1KMT2AGAAHPGD | |
| Fumaric Acid SCHEMBL9603164 | 0.84 | KDM4E (0.35) | GAA | |
| Fumaric Acid SCHEMBL9602985 | 0.84 | MAPT (0.33) | SMN1; SMN2MEN1KMT2AGAAHPGD | |
| Fumaric Acid SCHEMBL9603160 | 0.84 | KDM4E (0.35) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |