Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.32 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866052 | 0.93 | MCHR1 (0.34) | TOP1MCHR1ACHETP53POLB | |
| SCHEMBL9865229 | 0.91 | TOP1 (0.35) | TOP1HRH3MCHR1ACHEKCNH2 | |
| SCHEMBL9602580 | 0.87 | MCHR1 (0.39) | TOP1MCHR1ACHENPC1MAPK1 | |
| SCHEMBL9866395 | 0.87 | TOP1 (0.37) | TOP1HRH3MCHR1ACHEKCNH2 | |
| SCHEMBL9603147 | 0.84 | MCHR1 (0.35) | TOP1MCHR1ACHEHTTMEN1 | |
| SCHEMBL9602772 | 0.84 | MCHR1 (0.35) | TOP1MCHR1ACHEMAOB | |
| SCHEMBL10366166 | 0.83 | MEN1 (0.43) | HRH3KCNH2MAOBNPC1MAPK1 | |
| SCHEMBL9865917 | 0.81 | MAOA (0.34) | HRH3ACHES1PR1S1PR3MAOA | |
| Fumaric Acid SCHEMBL9867491 | 0.81 | ALDH1A1 (0.35) | MCHR1NPC1MAPK1RAB9AMEN1 | |
| Fumaric Acid SCHEMBL9867501 | 0.81 | ALDH1A1 (0.35) | MCHR1NPC1MAPK1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |