Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868107 | 0.75 | ALOX5 (0.58) | ALOX5ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9868637 | 0.75 | SMN1; SMN2 (0.45) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL9867554 | 0.75 | NPC1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL30943969 | 0.74 | LPL (0.48) | ALOX5ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9867347 | 0.72 | KDM4E (0.61) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL6233715 | 0.72 | PIK3R1 (0.63) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL31631303 | 0.71 | NPC1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL25028312 | 0.71 | ALOX5 (0.71) | ALOX5ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30648212 | 0.70 | CHRNA7 (0.47) | ALDH1A1HPGDHSD17B10NPC1RAB9A | |
| SCHEMBL27075892 | 0.70 | CHRNA7 (0.47) | ALDH1A1HPGDHSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |