Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 3/20 | 0.46 |
| ▸ | F3 | P13726 | 3/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | C1R | P00736 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867554 | 0.85 | NPC1 (0.50) | KDM4EELANETP53MAPTSMN1; SMN2 | |
| SCHEMBL9869172 | 0.78 | MAPT (0.47) | KDM4EF2MAPTSMN1; SMN2C1R | |
| SCHEMBL9646773 | 0.76 | KDM4E (1.00) | KDM4EF7F3F10F2 | |
| Iodide SCHEMBL11648822 | 0.75 | KDM4E (0.97) | KDM4EF7F3F10F2 | |
| Iodide SCHEMBL11648817 | 0.75 | KDM4E (0.97) | KDM4EF7F3F10F2 | |
| SCHEMBL9868637 | 0.74 | SMN1; SMN2 (0.45) | KDM4ETP53MAPTSMN1; SMN2RXFP1 | |
| SCHEMBL9866232 | 0.72 | ALOX5 (0.49) | KDM4EELANETP53THRBMAPT | |
| SCHEMBL28211198 | 0.71 | NPC1 (0.47) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL9866308 | 0.70 | CETP (0.43) | KDM4ESMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL31631303 | 0.70 | NPC1 (0.64) | KDM4ETP53MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |