Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867686 | 0.82 | NFE2L2 (0.33) | POLBPKMKMT2A | |
| SCHEMBL9866804 | 0.80 | POLB (0.47) | POLBALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL9866908 | 0.80 | ALDH1A1 (0.39) | POLBALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL9867938 | 0.79 | POLB (0.51) | POLBALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL9867680 | 0.78 | NFE2L2 (0.34) | ALDH1A1MAPK1 | |
| SCHEMBL9866318 | 0.78 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2HTTGAA | |
| SCHEMBL27350634 | 0.77 | POLB (0.49) | POLBALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL9865825 | 0.76 | NFE2L2 (0.33) | — | |
| SCHEMBL9867057 | 0.74 | ALDH1A1 (0.35) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL9865417 | 0.73 | SMN1; SMN2 (0.37) | POLBALDH1A1SMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |