Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 3/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867680 | 0.87 | NFE2L2 (0.34) | NFE2L2PNMT | |
| SCHEMBL9865825 | 0.82 | NFE2L2 (0.33) | NFE2L2 | |
| SCHEMBL9866236 | 0.82 | POLB (0.48) | POLBPKMKMT2A | |
| SCHEMBL9866675 | 0.78 | PNMT (0.35) | PNMTPIK3CDPIK3CBPIK3CGPKM | |
| SCHEMBL9866908 | 0.77 | ALDH1A1 (0.39) | POLBPKMKMT2A | |
| SCHEMBL9866318 | 0.76 | ALDH1A1 (0.36) | NFE2L2 | |
| SCHEMBL9866944 | 0.75 | FEN1 (0.35) | NFE2L2KIF18A | |
| SCHEMBL27350633 | 0.75 | PNMT (0.33) | PNMTPIK3CDPIK3CBPIK3CGPKM | |
| SCHEMBL9867665 | 0.74 | KEAP1 (0.43) | POLBPKMKMT2A | |
| SCHEMBL9867057 | 0.72 | ALDH1A1 (0.35) | NFE2L2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |