Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 8/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865825 | 0.90 | NFE2L2 (0.33) | NFE2L2CA12CA1CA2CA9 | |
| SCHEMBL9867686 | 0.87 | NFE2L2 (0.33) | NFE2L2PNMT | |
| SCHEMBL9866908 | 0.80 | ALDH1A1 (0.39) | CA12CA2CA9ALDH1A1 | |
| SCHEMBL9866236 | 0.78 | POLB (0.48) | MAPK1ALDH1A1 | |
| SCHEMBL9866318 | 0.78 | ALDH1A1 (0.36) | NFE2L2ALDH1A1 | |
| SCHEMBL9866944 | 0.77 | FEN1 (0.35) | NFE2L2 | |
| SCHEMBL9867057 | 0.74 | ALDH1A1 (0.35) | NFE2L2ALDH1A1 | |
| SCHEMBL9865417 | 0.73 | SMN1; SMN2 (0.37) | TDP1ALDH1A1 | |
| SCHEMBL9867665 | 0.73 | KEAP1 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL10374251 | 0.73 | ALDH1A1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |