Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.38 |
| ▸ | GLRB | P48167 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865969 | 0.81 | TRPV3 (0.45) | KAT8MAPK1ALDH1A1LMNAHPGD | |
| SCHEMBL9866236 | 0.80 | POLB (0.48) | POLBMAPK1ALDH1A1LMNAHPGD | |
| SCHEMBL9867413 | 0.79 | TRPV3 (0.46) | POLBKAT8MAPK1ALDH1A1LMNA | |
| SCHEMBL9866569 | 0.78 | AR (0.51) | POLBKAT8HPGDNPC1SMN1; SMN2 | |
| SCHEMBL9866681 | 0.78 | KAT8 (0.47) | KAT8ALDH1A1LMNATRPV3MEN1 | |
| SCHEMBL9865599 | 0.77 | KAT8 (0.41) | KAT8LMNAHPGDNPC1SMN1; SMN2 | |
| SCHEMBL9866578 | 0.76 | TRPV3 (0.44) | POLBKAT8MAPK1ALDH1A1LMNA | |
| SCHEMBL9865486 | 0.75 | KMT2A (0.43) | KAT8ALDH1A1SMN1; SMN2TRPV3HTT | |
| SCHEMBL9867938 | 0.75 | POLB (0.51) | POLBMAPK1ALDH1A1LMNAHPGD | |
| SCHEMBL9734839 | 0.74 | CA1 (0.50) | KAT8ALDH1A1KDM4ETRPV3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| CN-1042144-A | Pesticidal compound | ICI PLC (GB) | 1990-05-16 | — | — | CN | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |