Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867629 | 0.88 | ALDH1A1 (0.44) | CYP2C9SLC6A9CTNNB1WNT3AKMT2A | |
| SCHEMBL10439859 | 0.82 | ALDH1A1 (0.40) | EDNRAALOX15LMNASLC6A9KMT2A | |
| SCHEMBL9867484 | 0.78 | MAPT (0.47) | CYP2C9ALOX15LMNASLC6A9CTNNB1 | |
| SCHEMBL9869017 | 0.76 | ALOX5 (0.52) | ALOX15LMNAKMT2AMAPTHPGD | |
| SCHEMBL10439771 | 0.75 | MAPT (0.47) | CYP2C9ALOX15LMNASLC6A9CTNNB1 | |
| SCHEMBL11743754 | 0.72 | EDNRA (0.58) | EDNRAMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL9867505 | 0.71 | SMN1; SMN2 (0.50) | EDNRAALOX15LMNAKMT2AMAPT | |
| SCHEMBL30785082 | 0.71 | L3MBTL1 (0.53) | ALOX15LMNASLC6A9CTNNB1WNT3A | |
| SCHEMBL11454337 | 0.70 | CYP2C9 (0.67) | CYP2C9ALOX15LMNACTNNB1WNT3A | |
| SCHEMBL11435106 | 0.69 | CYP2C9 (0.69) | CYP2C9ALOX15LMNASLC6A9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006549-A | Antiinflammatory agents | MERCK & CO., INC. (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0399773-A1 | Novel 7-aroyl-4-hydroxy-3-methyl benzolfurans as dual inhibitors of cyclooxygenase and 5-lipoxygenase | MERCK & CO. INC. (US) | 1990-11-28 | — | — | EP | disclosed |