Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866663 | 0.87 | ALOX5 (0.47) | ALOX5PTGS1PTGS2MAPTALDH1A1 | |
| SCHEMBL9867950 | 0.84 | NPC1 (0.38) | ALOX5PTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL9868498 | 0.80 | GLRA3 (0.49) | ALOX5PTGS1PTGS2ALDH1A1HSD17B10 | |
| SCHEMBL9868574 | 0.79 | MCL1 (0.39) | ALOX5PTGS2LMNAMAPTALDH1A1 | |
| SCHEMBL9866780 | 0.79 | ALOX5 (0.55) | ALOX5PTGS1PTGS2ALOX15LMNA | |
| SCHEMBL9866669 | 0.76 | ALOX5 (0.40) | ALOX5PTGS1PTGS2ALOX15LMNA | |
| SCHEMBL10439859 | 0.76 | ALDH1A1 (0.40) | ALOX15LMNAMAPTALDH1A1PSMD14 | |
| SCHEMBL9866645 | 0.76 | EDNRA (0.50) | ALOX15LMNAMAPTALDH1A1PSMD14 | |
| SCHEMBL9867508 | 0.72 | NPC1 (0.45) | ALOX5MAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL10439698 | 0.70 | ALOX15 (0.48) | ALOX5PTGS1PTGS2ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006549-A | Antiinflammatory agents | MERCK & CO., INC. (US) | 1991-04-09 | — | — | US | disclosed |