Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866750 | 1.00 | CHRNB2 (0.38) | CHRNB2CHRNA4LMNAALDH1A1GAA | |
| SCHEMBL13654231 | 1.00 | CHRNB2 (0.38) | CHRNB2CHRNA4LMNAALDH1A1GAA | |
| Imidaclothiz SCHEMBL676082 | 0.81 | CHRNB2 (0.55) | CHRNB2CHRNA4LMNAALDH1A1GAA | |
| Imidaclothiz SCHEMBL238122 | 0.81 | CHRNB2 (0.55) | CHRNB2CHRNA4LMNAALDH1A1GAA | |
| Desmethylthiamethoxam SCHEMBL7173902 | 0.81 | CHRNB2 (0.40) | CHRNB2CHRNA4LMNAALDH1A1GAA | |
| SCHEMBL515504 | 0.81 | LMNA (0.38) | CHRNB2CHRNA4LMNAALDH1A1GAA | |
| SCHEMBL45483 | 0.81 | LMNA (0.38) | CHRNB2CHRNA4LMNAALDH1A1GAA | |
| SCHEMBL45484 | 0.81 | LMNA (0.38) | CHRNB2CHRNA4LMNAALDH1A1GAA | |
| Desmethylthiamethoxam SCHEMBL6445790 | 0.81 | CHRNB2 (0.40) | CHRNB2CHRNA4LMNAALDH1A1GAA | |
| Desmethylthiamethoxam SCHEMBL6445785 | 0.81 | CHRNB2 (0.40) | CHRNB2CHRNA4LMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032589-A | Insecticidal heterocyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-07-16 | — | — | US | claimed |