Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Desmethylthiamethoxam SCHEMBL7173902 | 1.00 | CHRNB2 (0.40) | CHRNB2CHRNA4MAPTLMNAALDH1A1 | |
| Desmethylthiamethoxam SCHEMBL6445785 | 1.00 | CHRNB2 (0.40) | CHRNB2CHRNA4MAPTLMNAALDH1A1 | |
| Imidaclothiz SCHEMBL676082 | 0.84 | CHRNB2 (0.55) | CHRNB2CHRNA4MAPTLMNAALDH1A1 | |
| Imidaclothiz SCHEMBL238122 | 0.84 | CHRNB2 (0.55) | CHRNB2CHRNA4MAPTLMNAALDH1A1 | |
| SCHEMBL7982213 | 0.82 | CHRNB2 (0.48) | CHRNB2CHRNA4MAPTLMNAALDH1A1 | |
| SCHEMBL10062415 | 0.81 | LMNA (0.37) | MAPTLMNAALDH1A1GAAKMT2A | |
| SCHEMBL6447070 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA4MAPTALDH1A1 | |
| SCHEMBL6723120 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA4MAPTALDH1A1 | |
| SCHEMBL9866741 | 0.81 | CHRNB2 (0.38) | CHRNB2CHRNA4MAPTLMNAALDH1A1 | |
| SCHEMBL9866750 | 0.81 | CHRNB2 (0.38) | CHRNB2CHRNA4MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884755-B2 | Pesticidal composition | SYNGENTA CROP PROTECTION, INC. (US) | 2005-04-26 | — | — | US | claimed |
| US-20030166618-A1 | Pesticidal composition | SENN ROBERT (CH) | 2003-09-04 | — | — | US | claimed |
| EP-0915656-B1 | PESTICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2003-07-23 | — | — | EP | claimed |
| EP-0900024-B1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2003-06-18 | — | — | EP | claimed |
| EP-0915656-A1 | PESTICIDAL COMPOSITION | Novartis AG (CH) | 1999-05-19 | — | — | EP | claimed |
| WO-1997040691-A1 | PESTICIDAL COMPOSITION | NOVARTIS AG (CH) | 1997-11-06 | — | — | WO | claimed |
| US-6884755-B2 | Pesticidal composition | SYNGENTA CROP PROTECTION, INC. (US) | 2005-04-26 | — | — | US | disclosed |
| US-20040122227-A1 | Cyclic guanidine derivatives and their use as pesticides | WAGNER KLAUS (DE) | 2004-06-24 | — | — | US | disclosed |
| US-6683028-B1 | Cyclic guanidine derivatives and their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-01-27 | — | — | US | disclosed |
| US-20030166618-A1 | Pesticidal composition | SENN ROBERT (CH) | 2003-09-04 | — | — | US | disclosed |
| EP-0915656-B1 | PESTICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2003-07-23 | — | — | EP | disclosed |
| EP-0900024-B1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2003-06-18 | — | — | EP | disclosed |
| US-6514954-B1 | For controlling insects or representatives of the order Acarina | SYNGENTA CROP PROTECTION, INC. | 2003-02-04 | — | — | US | disclosed |
| EP-0915656-A1 | PESTICIDAL COMPOSITION | Novartis AG (CH) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998006710-A1 | SUBSTITUTED 4-NITROIMINO-PERHYDRO-1,3,5-OXADIAZINE DERIVATIVES, THEIR USE AS PESTICIDES AND INTERMEDIATES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 1998-02-19 | — | — | WO | disclosed |
| WO-1997040691-A1 | PESTICIDAL COMPOSITION | NOVARTIS AG (CH) | 1997-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122227-A1 | Cyclic guanidine derivatives and their use as pesticides | PRMT1, GUCY1A1, GUCY1A2 | CHRNB2 527/4885CHRNA4 440/4885MAPT 4114/4885 |
| US-20030166618-A1 | Pesticidal composition | TUBA3C, DDT, TUBB3 | CHRNB2 453/4885CHRNA4 916/4885MAPT 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.