Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866879 | 0.88 | ALDH1A1 (0.42) | ALDH1A1HRH3KDM4EHTTCYP2D6 | |
| SCHEMBL9866841 | 0.87 | ALDH1A1 (0.41) | ALDH1A1KCNH2HRH3KDM4EHTT | |
| SCHEMBL8367322 | 0.79 | ADORA2A (0.36) | ALDH1A1MAPK1KCNH2LMNATSHR | |
| Hydrochloric Acid SCHEMBL8151433 | 0.78 | TLR8 (0.36) | ALDH1A1MAPK1KCNH2TSHRPOLB | |
| SCHEMBL10272811 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SIGMAR1MAPK1CYP1A2CHRM2 | |
| SCHEMBL9866166 | 0.76 | ALDH1A1 (0.36) | ALDH1A1CYP1A2KCNH2HRH3KDM4E | |
| SCHEMBL9867208 | 0.75 | SIGMAR1 (0.34) | ALDH1A1SIGMAR1HRH3KDM4EPOLB | |
| SCHEMBL9867170 | 0.75 | ALDH1A1 (0.38) | ALDH1A1CYP1A2KCNH2HRH3KDM4E | |
| SCHEMBL9867651 | 0.75 | PKM (0.44) | ALDH1A1MAPK1HRH3LMNAKDM4E | |
| SCHEMBL13587988 | 0.75 | TLR8 (0.39) | ALDH1A1KCNH2TSHRPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011838-A | Antiallergens, antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-04-30 | — | — | US | claimed |
| EP-0397615-A2 | Pharmacologically active 2-substituted 3-(2-ethoxyethyl) imidazo [4,5-b] pyridines and pharmaceutical compositions containing them | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-11-14 | — | — | EP | claimed |
| US-5011838-A | Antiallergens, antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-04-30 | — | — | US | disclosed |
| EP-0397615-A2 | Pharmacologically active 2-substituted 3-(2-ethoxyethyl) imidazo [4,5-b] pyridines and pharmaceutical compositions containing them | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-11-14 | — | — | EP | disclosed |