Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171036 | 0.80 | KMT2A (0.61) | HTR2BALDH1A1 | |
| SCHEMBL6771000 | 0.80 | ADAMTS4 (0.48) | ADAMTS4ALDH1A1NPSR1 | |
| SCHEMBL29910058 | 0.79 | L3MBTL1 (0.52) | CYTH2HSD17B1HSD17B2PKM | |
| SCHEMBL4945399 | 0.79 | L3MBTL1 (0.52) | CYTH2HSD17B1HSD17B2PKM | |
| SCHEMBL532021 | 0.79 | HTR2B (0.47) | HTR2BPTPN11PTPN1PTPN6ALDH1A1 | |
| SCHEMBL13543487 | 0.79 | CA1 (0.62) | HTR2BPTPN11PTPN1PTPN6 | |
| SCHEMBL12376750 | 0.79 | PGR (0.60) | HTR2BALDH1A1PKM | |
| SCHEMBL12089569 | 0.79 | CA2 (0.51) | HTR2BALDH1A1GFERNPSR1ALDH3A1 | |
| SCHEMBL265556 | 0.79 | HSD17B2 (0.49) | HTR2BALDH1A1GFERHSD17B2 | |
| SCHEMBL7913284 | 0.79 | HTR2B (0.52) | HTR2BALDH1A1GFERNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |