Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TNNI3K | Q59H18 | 4/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | UQCRB | P14927 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945399 | 1.00 | L3MBTL1 (0.52) | L3MBTL1TNNI3KEGFRTSHRCYTH2 | |
| SCHEMBL13362241 | 0.89 | HSD17B1 (0.56) | L3MBTL1TNNI3KEGFRTSHRHSD17B2 | |
| SCHEMBL2242660 | 0.85 | L3MBTL1 (0.61) | L3MBTL1TNNI3KEGFRLMNAPTBP1 | |
| SCHEMBL27743877 | 0.82 | CA2 (0.59) | CYTH2LMNAHSD17B2HSD17B1PKM | |
| SCHEMBL13614682 | 0.80 | TSHR (0.52) | L3MBTL1TNNI3KEGFRTSHRLMNA | |
| SCHEMBL9866942 | 0.79 | HTR2B (0.49) | CYTH2HSD17B2HSD17B1PKM | |
| SCHEMBL2543543 | 0.79 | PKM (0.56) | TSHRCYTH2PKMGAASMN1; SMN2 | |
| SCHEMBL29403896 | 0.79 | ALDH1A1 (0.50) | TSHRCYTH2LMNAHSD17B2HSD17B1 | |
| SCHEMBL8272569 | 0.78 | TNNI3K (0.60) | L3MBTL1TNNI3KEGFRLMNAPTBP1 | |
| SCHEMBL29547938 | 0.78 | KMT2A (0.67) | L3MBTL1TNNI3KEGFRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267276-A1 | NLRP MODULATORS | NOVARTIS INFLAMMASOME RESEARCH, INC. | 2022-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267276-A1 | NLRP MODULATORS | NLRP1, NRP1, NR4A3 | L3MBTL1 4865/4885TNNI3K 2087/4885EGFR 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.