Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608574 | 0.84 | KCNA5 (0.46) | TERTKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL2051650 | 0.72 | KMT2A (0.50) | KDM4EMAPTALDH1A1NPC1PKM | |
| SCHEMBL9867136 | 0.69 | ALDH1A1 (0.42) | MAPTALDH1A1MAPK1POLBSMN1; SMN2 | |
| SCHEMBL9266484 | 0.66 | MAPT (0.50) | KDM4EMAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL23035059 | 0.65 | ALDH1A1 (0.43) | TERTKDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL19868760 | 0.65 | CYP2C19 (0.48) | MAPTALDH1A1NPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL30259745 | 0.63 | MAPT (0.54) | KDM4EMAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL27941669 | 0.63 | CYP2C19 (0.53) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL11164693 | 0.63 | L3MBTL1 (0.53) | TERTMAPTALDH1A1NPC1PKM | |
| SCHEMBL6741700 | 0.62 | HSD17B2 (0.50) | TERTKDM4EMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073428-B1 | DIHYDROXYPHENYL DERIVATIVES FOR HEPATOPROTECTION AND TREATMENT OF LIVER DISEASES | CHOONGWAE PHARMA CO LTD (KR) | 2004-10-27 | — | — | EP | disclosed |
| US-6693126-B2 | OXIME-SUBSTITUTED M-DIHYDROXYBENZENE OR 1,3-BENZODIOXOLE COMPOUND OF GIVEN FORMULA AND AN INERT CARRIER | CHOONGWAE PHARM. CO., LTD. (KR) | 2004-02-17 | — | — | US | disclosed |
| US-20030083326-A1 | Dihydroxyphenyl derivatives for hepatoprotection and treatment of liver diseases | CHOONGWAE PHARM. CO., LTD. (KR) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083326-A1 | Dihydroxyphenyl derivatives for hepatoprotection and treatment of liver diseases | SLC10A1, SLC10A2, ABCB11 | TERT 4665/4885KDM4E 3364/4885MAPT 3502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.