Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866342 | 0.93 | MCHR1 (0.36) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL9866572 | 0.92 | MMP12 (0.40) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL9865465 | 0.89 | MCHR1 (0.38) | CA12CA1CA2CA9MCHR1 | |
| SCHEMBL9601577 | 0.89 | MCHR1 (0.37) | CA12CA1CA2CA9MCHR1 | |
| SCHEMBL9602979 | 0.87 | MCHR1 (0.43) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL9867683 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MCHR1MAPTGAAL3MBTL1 | |
| SCHEMBL9866266 | 0.81 | MCHR1 (0.42) | ALDH1A1MCHR1MAPTGAAL3MBTL1 | |
| SCHEMBL9867236 | 0.80 | MCHR1 (0.44) | ALDH1A1MCHR1MAPTGAAL3MBTL1 | |
| SCHEMBL9866081 | 0.80 | HRH3 (0.33) | CA12CA1CA2CA9MMP12 | |
| SCHEMBL9602271 | 0.79 | MCHR1 (0.39) | ALDH1A1MCHR1MAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |