SCHEMBL5658052

SCHEMBL5658052

O=C(O)Cc1ccc(NC(=O)c2cc(Cl)cc(Cl)c2O)cc1

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.64
TBXAS1 P24557 1/20 0.64
MAPK1 P28482 1/20 0.64
PTGS2 P35354 1/20 0.64
MAPK14 Q16539 1/20 0.64
STK39 Q9UEW8 10/20 0.63
KDM4E B2RXH2 1/20 0.58
PARG Q86W56 2/20 0.55
NR1H4 Q96RI1 2/20 0.54
PNLIP P16233 1/20 0.53
FFAR1 O14842 1/20 0.52
KLKB1 P03952 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5658654 0.87 PTGS1 (0.61) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL5655299 0.85 PTGS1 (0.59) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL649911 0.84 PTGS1 (0.77) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL29375129 0.84 PTGS1 (0.77) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL9868077 0.83 STK39 (0.77) PTGS1TBXAS1MAPK1PTGS2MAPK14
Hydrochloric Acid SCHEMBL11777767 0.81 STK39 (0.75) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL19077944 0.81 PTGS1 (0.60) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL25413048 0.80 PTGS1 (0.71) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL10457403 0.80 PARG (0.71) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL11692717 0.80 PTGS1 (0.71) PTGS1TBXAS1MAPK1PTGS2MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
US-20260077020-A1 ORAL PEPTIDE PHARMACEUTICAL COMPOSITION THAT FACILITATES ENHANCED ORAL ABSORPTION LE ROUX DANIELLE MARIE (US) 2026-03-19 US disclosed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO disclosed
US-20090324540-A1 COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2009-12-31 US disclosed
US-20090324540-A1 COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2009-12-31 US disclosed
US-7553872-B2 Compounds and compositions for delivering active agents EMISPHERE TECHNOLOGIES, INC. (US) 2009-06-30 US disclosed
US-7553872-B2 Compounds and compositions for delivering active agents EMISPHERE TECHNOLOGIES, INC. (US) 2009-06-30 US disclosed
US-7071214-B2 Compounds and compositions for delivering active agents EMISPHERE TECHNOLOGIES, INC. (US) 2006-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260077020-A1 ORAL PEPTIDE PHARMACEUTICAL COMPOSITION THAT FACILITATES ENHANCED ORAL ABSORPTION VIP, GIPR, SLC10A2 PTGS1 948/4885TBXAS1 4259/4885MAPK1 2609/4885
US-20090324540-A1 COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS ABCB4, ABCB7, ALPP PTGS1 1784/4885TBXAS1 1375/4885MAPK1 4648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.