Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285594 | 0.88 | CTNNB1 (0.37) | MAOAMAOBALDH1A1HPGD | |
| SCHEMBL9524640 | 0.79 | SLC9A1 (0.38) | NOTUMSLC9A1KEAP1SLC6A4CYP19A1 | |
| SCHEMBL11774332 | 0.76 | NR1H2 (0.40) | MAOAMAOBCYP11B1 | |
| Bromide SCHEMBL9867732 | 0.73 | SLC9A1 (0.45) | NOTUMSLC9A1KEAP1SLC6A4NSD2 | |
| SCHEMBL11776643 | 0.69 | ADORA2A (0.38) | ALDH1A1HSD17B10 | |
| SCHEMBL12560105 | 0.66 | SLC9A1 (0.50) | NOTUMSLC9A1KEAP1SLC6A4CYP19A1 | |
| SCHEMBL3279598 | 0.66 | TPH1 (0.37) | MAOAMAOBALDH1A1 | |
| SCHEMBL13180099 | 0.66 | HSP90AA1 (0.48) | MAOAMAOBALDH1A1HPGD | |
| SCHEMBL27661677 | 0.65 | KEAP1 (0.46) | NOTUMSLC9A1KEAP1SLC6A4CYP19A1 | |
| SCHEMBL11779637 | 0.65 | HSP90AA1 (0.38) | MAOAMAOBCYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039677-A | Estrogen inhibitor | JANSSEN PHARMACEUTICA N.V. (CA) | 1991-08-13 | — | — | US | disclosed |